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Can Hiccups Be Cured?

By Sadia Naeem
7 May 2010

A man walks into a pharmacy and asks the pharmacist if he has anything for hiccups. The pharmacist raises his hand and slaps the man across his face.

“What did you do that for?!” cried the man.

“Well, you don’t have the hiccups now, do you?” replied the pharmacist.

“No,” said the man, thrusting a finger at the door. “But my wife in the car still does!”

Don’t deny it, I know you’re laughing. At first I thought I’d post a pharmacy-related joke to give fellow pharmacy students something to raise their spirits, as the exam period is excruciatingly close and no doubt many of you, if the University of Manchester’s library is anything to go by, are working hard and late into the night in order to satisfy your brain’s constant self-criticism of never having done enough revision. I did laugh when I read this joke; although, if you ask anyone who knows me they will probably tell you that I laugh at anything really.

Funny, though, how training to become a pharmacist makes you analyse small things in certain ways. Obviously, hiccups are not at the top of pharmaceutical companies’ list of potential treatment research areas at the moment, but you do tend to wonder. For example, whatever I’m feeling or suffering from, whether it’s laziness or anger, procrastination or indeed the hiccups, I more often than not think “there must be a drug for this”.

The human body is an amazing labyrinth of discovered and undiscovered genius. There are many receptors, carrier proteins and other such structures within the body that can be and have been manipulated in order to cure varying conditions affecting humans. Many still remain to be discovered; most of the human genome had been mapped by 2003, a comparatively recent breakthrough, which leaves much hope for the future. The first lobotomies on live patients, before being retracted, began in 1946 to apparently cure mental health illnesses, so you never know, maybe one day scientists will discover a way to “cure” procrastination and other such blockbuster areas (well, from a student’s viewpoint anyway) a little less severely than by cutting connections to the brain!

Funny

Hey sadia, your joke really cheered me up, i read the first part of your blog and i couldn't stop laughing... keep them coming, raise our spirits as i've got just 9 days till my exams start.

Hi Andrew, glad you liked

Hi Andrew, glad you liked it. I may make pharmacy jokes the subject of my next blog, so watch this space! Good luck with your upcoming exams :)

Hiccups

The human body is an amazing labrinth of human genius and what is outside the 'normal' range does not necessarily need to be treated to be brought within what we perceive to be normal. That rich diversity is what makes us human and very special as a species.

So, laziness or anger or procrastination may in actual fact be good things. Time to reflect on a decison making process, time to rest the body and mind are not negative attributes in ALL circumstances, and neither is anger.

Hiccups however is a very debilitaing problem. I have unfortunately suffered post-operatively on 4 seperate occasions and the hiccups are persistent and lasted for nearly 2 weeks. The lack of sleep, not being able to eat properly does not help the post operative recovery process. I 'advised' from the start that I needed chlorpromazine, and after the clinical staff trying the remedies that have NO clinical evidence to support them (eg breathing in and out of a syringe, and haloperidol) my consultant returned from leave and is of a similar age to myself agreed and supported my decison. Chlorpromazine 25-50mg tds does cure persistent hiccups. It is licensed as such, and I first read about this use some 30+ years ago.

Do not feel guilty about laziness, anger or procrastination, a little of anything in moderation does not harm but may be good. Fools rush in where Angels fear to tread. 

Colin Ranshaw

 

 

Good Point Colin.

Good Point Colin Ranshaw. I watched a documentary on the bbc about 4 months ago, it's called "the man who can't stop hiccuping", this man hiccuped for about 3 years non-stop, the hiccups was also violent. This man is called Chris Sands.

According to this documentary, his hiccups was due to a tumour in his brain, which was discovered when he visited a hospital in japan, after having countless meetings with various consultants from the NHS.

Colin, you should try to watch the documentary when you are less busy. http://www.bbc.co.uk/programmes/b00pzch7. Good topic to tackle Sadia.

Chlorpromazine

Thanks for that information Colin. I had no idea that one of the indications for chlorpromazine was intractable hiccups...I was only aware of its antipsychotic activity, having studied it during my Medicinal Chemistry module. What you say is very true though, regarding the things that make us human.

An interesting fact...I just read up on the man Andrew mentioned and found that the longest bout of hiccups was suffered by a man called Charles Osbourne for 68 years! They apparently stopped as mysteriously as they began.