Drug interactions: Interactions between fentanyl and drugs that inhibit CYP3A4
A theoretical patient, Mr X is has been taking morphine up to 100mg daily for cancer-related pain but, since his pain is still not properly controlled, a transdermal fentanyl patch is prescribed at a dose of 25µg/h. He has a past medical history of angina, high blood pressure and osteoarthritis, and his long-term medication includes aspirin, simvastatin, ramipril, diltiazem, isosorbide mononitrate and glucosamine/chondroitin
Anaesthesia and surgical pain relief — the ideal general anaesthetic agent
This special feature reviews some of the drugs used in the surgical and post-surgical periods. This first part examines general anaesthetics and compares the properties of currently available agents with the profile of the ideal general anaesthetic
Peri-operative medication (9 parts)
A nine-part series considering various aspects of treatment in the the peri-operative period.
